Anxiolytic Potentiality of Tamarindus indica Flowers

Tamarindus indica (Fabaceae) have been using in traditional medicine to cure various diseases, including mental stress and anxiousness. The current study was aimed evaluate phytochemical analysis anxiolytic activity of flower extracts (n-Hexane, Ethyl acetate, Chloroform methanol) different animal models such as elevated plus-maze, mirror chamber, light/dark, hole board tests. had showed presence constituents. mice were given two doses these see whether they any anti-anxiety effects an maze-plus experiment. methanol extract prominent compared other extracts. used for further column chromatography four fractions (F1-F4) separated their tested investigate the properties. fraction F3 better preparative thin layer three isolated. (F3.2) identified flavonoid through tests Fourier transform infrared, Nuclear Magnetic Resonance, data 3570 (-OH Str, Ar-OH) 1753(C=O Str). F3.2 has properties (4.8±0.31 7.2±0.30 secs) by plus maze test. Fraction at 80 mg/kg dose administered orally a considerable effect on From results study, there is need do thorough investigation finding out mechanism action it either serotonergic or GABAergic pathway F3.2. may be first report about flavonoids showing